# Comparing the Safety and Effectiveness of Topiramate With the Safety and Effectiveness of Amitriptyline in Preventing Migraine Headaches

> **NCT00210821** · PHASE3 · COMPLETED · sponsor: **Johnson & Johnson Pharmaceutical Research & Development, L.L.C.** · enrollment: 347 (actual)

## Conditions studied

- Migraine
- Headache

## Interventions

- **DRUG:** topiramate

## Key facts

- **NCT ID:** NCT00210821
- **Lead sponsor:** Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-02
- **Primary completion:** —
- **Final completion:** 2005-11
- **Target enrollment:** 347 (ACTUAL)
- **Last updated:** 2011-06-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00210821

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00210821, "Comparing the Safety and Effectiveness of Topiramate With the Safety and Effectiveness of Amitriptyline in Preventing Migraine Headaches". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT00210821. Licensed CC0.

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