Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

Conditions

• Childhood Acute Promyelocytic Leukemia (M3)
• Childhood Atypical Teratoid/Rhabdoid Tumor
• Childhood Burkitt Lymphoma
• Childhood Chronic Myelogenous Leukemia
• Childhood Diffuse Large Cell Lymphoma
• Childhood Immunoblastic Large Cell Lymphoma
• Juvenile Myelomonocytic Leukemia
• Recurrent Childhood Acute Lymphoblastic Leukemia
• Recurrent Childhood Acute Myeloid Leukemia
• Recurrent Childhood Grade III Lymphomatoid Granulomatosis
• Recurrent Childhood Large Cell Lymphoma
• Recurrent Childhood Lymphoblastic Lymphoma
• Recurrent Childhood Medulloblastoma
• Recurrent Childhood Small Noncleaved Cell Lymphoma
• Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
• Recurrent Neuroblastoma
• Recurrent/Refractory Childhood Hodgkin Lymphoma
• Relapsing Chronic Myelogenous Leukemia
• Unspecified Childhood Solid Tumor, Protocol Specific

Interventions

• DRUG: vorinostat
• DRUG: isotretinoin

Sponsor

National Cancer Institute (NCI)