# Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients

> **NCT00221845** · PHASE3 · COMPLETED · sponsor: **Heidelberg University** · enrollment: 400 (actual)

## Conditions studied

- Children
- Chronic Renal Failure
- Hypertension
- Acquired Kidney Disease
- Congenital Kidney Disease

## Interventions

- **DRUG:** ACE Inhibition
- **DRUG:** Intensified Blood Pressure Control
- **DRUG:** Add-on Angiotensin Receptor Blockade

## Key facts

- **NCT ID:** NCT00221845
- **Lead sponsor:** Heidelberg University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1998-01
- **Primary completion:** 2007-07
- **Final completion:** 2010-01
- **Target enrollment:** 400 (ACTUAL)
- **Last updated:** 2010-01-12

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00221845

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00221845, "Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT00221845. Licensed CC0.

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