# Chromosome 18 Clinical Research Center

> **NCT00227253** · — · RECRUITING · sponsor: **The University of Texas Health Science Center at San Antonio** · enrollment: 4000 (estimated)

## Conditions studied

- Chromosome Aberrations
- Growth Hormone Deficiency
- Hypomyelination

## Interventions

- **PROCEDURE:** Determination of growth hormone status
- **PROCEDURE:** Measurement of growth, thyroid and sex hormone levels
- **PROCEDURE:** Behavior and neuropsychometric evaluations
- **PROCEDURE:** Audiological and ear, nose and throat examination
- **PROCEDURE:** Magnetic resonance imaging of the brain
- **PROCEDURE:** Dysmorphology evaluation
- **PROCEDURE:** Neurology examination
- **PROCEDURE:** Dental evaluation
- **PROCEDURE:** Speech pathology evaluation
- **PROCEDURE:** Psychiatric evaluation
- **PROCEDURE:** Orthopedic evaluation
- **PROCEDURE:** Ophthalmologic evaluation
- **PROCEDURE:** Gastrointestinal evaluation

## Key facts

- **NCT ID:** NCT00227253
- **Lead sponsor:** The University of Texas Health Science Center at San Antonio
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 1993-09
- **Primary completion:** 2040-12
- **Final completion:** 2040-12
- **Target enrollment:** 4000 (ESTIMATED)
- **Last updated:** 2026-01-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00227253

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00227253, "Chromosome 18 Clinical Research Center". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00227253. Licensed CC0.

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