# Lupus Immunosuppressive/Immunomodulatory Therapy or Stem Cell Transplant (LIST)

> **NCT00230035** · PHASE2 · WITHDRAWN · sponsor: **National Institute of Allergy and Infectious Diseases (NIAID)**

## Conditions studied

- Systemic Lupus Erythematosus

## Interventions

- **PROCEDURE:** Leukapheresis
- **PROCEDURE:** Non-myeloablative high dose immunosuppressive therapy conditioning (HDIT)
- **PROCEDURE:** Autologous CD34+HPC transplantation (HSCT)
- **PROCEDURE:** Plasmapheresis
- **DRUG:** Rabbit anti-thymocyte globulin
- **DRUG:** Methylprednisolone
- **DRUG:** Growth colony stimulating factor (G-CSF)
- **DRUG:** Corticosteroids
- **DRUG:** Mycophenolate mofetil
- **DRUG:** Azathioprine
- **DRUG:** Intravenous immunoglobulin
- **DRUG:** Methotrexate
- **DRUG:** Rituximab
- **DRUG:** Leflunomide

## Key facts

- **NCT ID:** NCT00230035
- **Lead sponsor:** National Institute of Allergy and Infectious Diseases (NIAID)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2005-09
- **Primary completion:** —
- **Final completion:** —
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Recommended by DSMB due to lack of accrual
- **Last updated:** 2013-02-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00230035

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00230035, "Lupus Immunosuppressive/Immunomodulatory Therapy or Stem Cell Transplant (LIST)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00230035. Licensed CC0.

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