# Dose-escalating Safety Study in Subjects on Stable Statin Therapy

> **NCT00231569** · PHASE2 · COMPLETED · sponsor: **Kastle Therapeutics, LLC** · enrollment: 74 (actual)

## Conditions studied

- Hypercholesterolemia

## Interventions

- **DRUG:** ISIS 301012 or Placebo
- **DRUG:** ISIS 301012 or Placebo
- **DRUG:** ISIS 301012 or Placebo
- **DRUG:** ISIS 301012 or Placebo
- **DRUG:** ISIS 301012 or Placebo
- **DRUG:** ISIS 301012 or Placebo
- **DRUG:** ISIS 301012 or Placebo

## Key facts

- **NCT ID:** NCT00231569
- **Lead sponsor:** Kastle Therapeutics, LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-09
- **Primary completion:** 2007-06
- **Final completion:** 2007-12
- **Target enrollment:** 74 (ACTUAL)
- **Last updated:** 2016-08-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00231569

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00231569, "Dose-escalating Safety Study in Subjects on Stable Statin Therapy". Retrieved via AI Analytics 2026-07-15 from https://api.ai-analytics.org/clinical/NCT00231569. Licensed CC0.

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