# A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease

> **NCT00235716** · PHASE3 · COMPLETED · sponsor: **US Department of Veterans Affairs** · enrollment: 613 (actual)

## Conditions studied

- Alzheimer's Disease

## Interventions

- **DRUG:** dl-alpha-tocopherol
- **DRUG:** Memantine
- **DRUG:** dl-alpha-tocopherol
- **DRUG:** Memantine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00235716
- **Lead sponsor:** US Department of Veterans Affairs
- **Sponsor class:** FED
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-08
- **Primary completion:** 2012-09
- **Final completion:** 2012-10
- **Target enrollment:** 613 (ACTUAL)
- **Last updated:** 2014-07-23

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00235716

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00235716, "A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT00235716. Licensed CC0.

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