# The Nitrate and Bone Study: Effects of Nitrates on Osteoporosis

> **NCT00252421** · PHASE3 · COMPLETED · sponsor: **University of Toronto** · enrollment: 243 (actual)

## Conditions studied

- Osteoporosis

## Interventions

- **DRUG:** Nitroglycerin ointment 15 mg/day daily for 24 month
- **DRUG:** Placebo ointment daily for 24 month

## Key facts

- **NCT ID:** NCT00252421
- **Lead sponsor:** University of Toronto
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-10
- **Primary completion:** 2010-06
- **Final completion:** 2010-07
- **Target enrollment:** 243 (ACTUAL)
- **Last updated:** 2014-05-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00252421

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00252421, "The Nitrate and Bone Study: Effects of Nitrates on Osteoporosis". Retrieved via AI Analytics 2026-09-21 from https://api.ai-analytics.org/clinical/NCT00252421. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
