# Treatment of Early Aggressive Rheumatoid Arthritis (TEAR)

> **NCT00259610** · PHASE4 · COMPLETED · sponsor: **University of Alabama at Birmingham** · enrollment: 755 (actual)

## Conditions studied

- Rheumatoid Arthritis

## Interventions

- **DRUG:** methotrexate
- **DRUG:** sulfasalazine
- **DRUG:** hydroxychloroquine
- **DRUG:** etanercept

## Key facts

- **NCT ID:** NCT00259610
- **Lead sponsor:** University of Alabama at Birmingham
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-05
- **Primary completion:** 2009-06
- **Final completion:** 2009-06
- **Target enrollment:** 755 (ACTUAL)
- **Last updated:** 2014-07-17

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00259610

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00259610, "Treatment of Early Aggressive Rheumatoid Arthritis (TEAR)". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT00259610. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
