# Radiation Therapy, Pemetrexed Disodium, and Carboplatin in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed By Surgery

> **NCT00268437** · PHASE2 · TERMINATED · sponsor: **Alliance for Clinical Trials in Oncology** · enrollment: 27 (actual)

## Conditions studied

- Esophageal Cancer

## Interventions

- **DRUG:** carboplatin
- **DRUG:** Pemetrexed
- **PROCEDURE:** conventional surgery
- **PROCEDURE:** neoadjuvant therapy
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00268437
- **Lead sponsor:** Alliance for Clinical Trials in Oncology
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2006-04
- **Primary completion:** 2008-01
- **Final completion:** 2015-03
- **Target enrollment:** 27 (ACTUAL)
- **Why stopped:** Trial closed early because, during an interim analysis, the primary endpoint fell short.
- **Last updated:** 2016-07-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00268437

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00268437, "Radiation Therapy, Pemetrexed Disodium, and Carboplatin in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed By Surgery". Retrieved via AI Analytics 2026-08-11 from https://api.ai-analytics.org/clinical/NCT00268437. Licensed CC0.

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