Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

NCT00272870 · clinicaltrials.gov ↗

PHASE1

Phase

TERMINATED

Status

1

Enrollment

OTHER

Sponsor class

Stopped Slow accrual; drug availability

Conditions

Glioblastoma Multiforme (WHO Grade IV)
Anaplastic Astrocytoma (WHO Grade III)

Interventions

DRUG: 06Benzylguanine
GENETIC: MGMT P140K
DEVICE: Meltenyi CliniMacs

Sponsor

Children's Hospital Medical Center, Cincinnati