# Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma

> **NCT00275106** · PHASE3 · TERMINATED · sponsor: **Children's Cancer and Leukaemia Group** · enrollment: 600 (estimated)

## Conditions studied

- Lymphoma

## Interventions

- **DRUG:** asparaginase
- **DRUG:** cyclophosphamide
- **DRUG:** cytarabine
- **DRUG:** daunorubicin hydrochloride
- **DRUG:** dexamethasone
- **DRUG:** doxorubicin hydrochloride
- **DRUG:** leucovorin calcium
- **DRUG:** mercaptopurine
- **DRUG:** methotrexate
- **DRUG:** prednisolone
- **DRUG:** thioguanine
- **DRUG:** vincristine sulfate
- **PROCEDURE:** radiation therapy

## Key facts

- **NCT ID:** NCT00275106
- **Lead sponsor:** Children's Cancer and Leukaemia Group
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2004-09
- **Primary completion:** 2009-12
- **Final completion:** 2012-08
- **Target enrollment:** 600 (ESTIMATED)
- **Why stopped:** Withdrawn due to an excess of toxic deaths
- **Last updated:** 2013-07-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00275106

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00275106, "Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00275106. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
