# TNF-alpha Directed Therapy in Asthma

> **NCT00278083** · PHASE2 · COMPLETED · sponsor: **Imperial College London** · enrollment: 40 (—)

## Conditions studied

- Asthma

## Interventions

- **DRUG:** Study drug administration
- **PROCEDURE:** Tuberculin intradermal skin test
- **PROCEDURE:** Lung function test for FEV1
- **PROCEDURE:** Asthma symptom scores diary
- **PROCEDURE:** Quality of life diary
- **PROCEDURE:** Breath nitric oxide
- **PROCEDURE:** Breath condensate
- **PROCEDURE:** Sputum induction
- **PROCEDURE:** Blood sampling
- **PROCEDURE:** Urinalysis

## Key facts

- **NCT ID:** NCT00278083
- **Lead sponsor:** Imperial College London
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2001-10
- **Primary completion:** —
- **Final completion:** 2004-04
- **Target enrollment:** 40 (—)
- **Last updated:** 2023-09-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00278083

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00278083, "TNF-alpha Directed Therapy in Asthma". Retrieved via AI Analytics 2026-08-03 from https://api.ai-analytics.org/clinical/NCT00278083. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*