# Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas

> **NCT00278278** · PHASE3 · UNKNOWN · sponsor: **German Society for Pediatric Oncology and Hematology GPOH gGmbH** · enrollment: 150 (estimated)

## Conditions studied

- Brain and Central Nervous System Tumors

## Interventions

- **DRUG:** cisplatin
- **DRUG:** etoposide
- **DRUG:** ifosfamide
- **DRUG:** lomustine
- **DRUG:** methotrexate
- **DRUG:** prednisone
- **DRUG:** vincristine sulfate

## Key facts

- **NCT ID:** NCT00278278
- **Lead sponsor:** German Society for Pediatric Oncology and Hematology GPOH gGmbH
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2003-09
- **Primary completion:** 2010-03
- **Final completion:** —
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2013-12-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00278278

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00278278, "Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT00278278. Licensed CC0.

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