# Fludarabine and Cyclophosphamide With or Without Rituximab in Patients With Previously Untreated Chronic B-Cell Lymphocytic Leukemia

> **NCT00281918** · PHASE3 · COMPLETED · sponsor: **Hoffmann-La Roche** · enrollment: 817 (actual)

## Conditions studied

- Leukemia

## Interventions

- **DRUG:** Rituximab
- **DRUG:** Cyclophosphamide
- **DRUG:** Fludarabine Phosphate

## Key facts

- **NCT ID:** NCT00281918
- **Lead sponsor:** Hoffmann-La Roche
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2003-07
- **Primary completion:** 2007-07
- **Final completion:** 2011-10
- **Target enrollment:** 817 (ACTUAL)
- **Last updated:** 2013-09-19

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00281918

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00281918, "Fludarabine and Cyclophosphamide With or Without Rituximab in Patients With Previously Untreated Chronic B-Cell Lymphocytic Leukemia". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00281918. Licensed CC0.

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