# Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors

> **NCT00281944** · PHASE1 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 42 (actual)

## Conditions studied

- Childhood Central Nervous System Choriocarcinoma
- Childhood Central Nervous System Embryonal Tumor
- Childhood Central Nervous System Germ Cell Tumor
- Childhood Central Nervous System Germinoma
- Childhood Central Nervous System Mixed Germ Cell Tumor
- Childhood Central Nervous System Teratoma
- Childhood Central Nervous System Yolk Sac Tumor
- Recurrent Childhood Brain Stem Glioma
- Recurrent Childhood Central Nervous System Embryonal Tumor
- Unspecified Childhood Solid Tumor, Protocol Specific

## Interventions

- **DRUG:** oxaliplatin
- **DRUG:** fluorouracil
- **DRUG:** leucovorin calcium
- **OTHER:** pharmacological study
- **PROCEDURE:** positron emission tomography
- **PROCEDURE:** computed tomography

## Key facts

- **NCT ID:** NCT00281944
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-09
- **Primary completion:** 2009-05
- **Final completion:** —
- **Target enrollment:** 42 (ACTUAL)
- **Last updated:** 2013-05-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00281944

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00281944, "Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors". Retrieved via AI Analytics 2026-08-03 from https://api.ai-analytics.org/clinical/NCT00281944. Licensed CC0.

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