# Randomized On-X Anticoagulation Trial

> **NCT00291525** · NA · COMPLETED · sponsor: **On-X Life Technologies, Inc.** · enrollment: 977 (actual)

## Conditions studied

- Heart Valve Disease

## Interventions

- **DEVICE:** On-X valve using reduced anticoagulation
- **DEVICE:** On-X Valve with Standard warfarin Therapy

## Key facts

- **NCT ID:** NCT00291525
- **Lead sponsor:** On-X Life Technologies, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-06-06
- **Primary completion:** 2023-08-08
- **Final completion:** 2023-12-29
- **Target enrollment:** 977 (ACTUAL)
- **Last updated:** 2024-12-24

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00291525

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00291525, "Randomized On-X Anticoagulation Trial". Retrieved via AI Analytics 2026-06-30 from https://api.ai-analytics.org/clinical/NCT00291525. Licensed CC0.

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