# Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain

> **NCT00293358** · PHASE3 · COMPLETED · sponsor: **Children's Cancer and Leukaemia Group** · enrollment: 500 (estimated)

## Conditions studied

- Brain and Central Nervous System Tumors

## Interventions

- **DRUG:** carboplatin
- **DRUG:** cisplatin
- **DRUG:** etoposide phosphate
- **DRUG:** ifosfamide
- **PROCEDURE:** adjuvant therapy
- **PROCEDURE:** conventional surgery
- **PROCEDURE:** neoadjuvant therapy
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00293358
- **Lead sponsor:** Children's Cancer and Leukaemia Group
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1997-01
- **Primary completion:** —
- **Final completion:** 2006-12
- **Target enrollment:** 500 (ESTIMATED)
- **Last updated:** 2013-09-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00293358

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00293358, "Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain". Retrieved via AI Analytics 2026-08-03 from https://api.ai-analytics.org/clinical/NCT00293358. Licensed CC0.

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