# Mineralocorticoid Receptor in the Treatment of Severe Depression

> **NCT00295347** · NA · COMPLETED · sponsor: **Universitätsklinikum Hamburg-Eppendorf** · enrollment: 65 (estimated)

## Conditions studied

- Major Depression

## Interventions

- **DRUG:** Spironolactone
- **DRUG:** fludrocortisone
- **DRUG:** escitalopram

## Key facts

- **NCT ID:** NCT00295347
- **Lead sponsor:** Universitätsklinikum Hamburg-Eppendorf
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-12
- **Primary completion:** 2008-06
- **Final completion:** 2008-06
- **Target enrollment:** 65 (ESTIMATED)
- **Last updated:** 2017-05-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00295347

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00295347, "Mineralocorticoid Receptor in the Treatment of Severe Depression". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00295347. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*