Donor Stem Cell Transplant in Treating Young Patients With Myelodysplastic Syndrome, Leukemia, Bone Marrow Failure Syndrome, or Severe Immunodeficiency Disease
Conditions
- Congenital Amegakaryocytic Thrombocytopenia
- Leukemia
- Myelodysplastic Syndromes
- Severe Congenital Neutropenia
Interventions
- BIOLOGICAL: anti-thymocyte globulin
- BIOLOGICAL: therapeutic allogeneic lymphocytes
- DRUG: fludarabine phosphate
- DRUG: thiotepa
- PROCEDURE: allogeneic bone marrow transplantation
- PROCEDURE: allogeneic hematopoietic stem cell transplantation
- PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
- RADIATION: total-body irradiation
Sponsor
University of California, San Francisco
Collaborators