Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders

NCT00301834 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

35

Enrollment

OTHER

Sponsor class

Conditions

Congenital Amegakaryocytic Thrombocytopenia
Diamond-blackfan Anemia
Leukemia
Myelodysplastic Syndromes
Severe Congenital Neutropenia

Interventions

BIOLOGICAL: alemtuzumab
DRUG: busulfan
DRUG: cyclosporine
DRUG: fludarabine phosphate
DRUG: methotrexate
DRUG: methylprednisolone
PROCEDURE: allogeneic bone marrow transplantation
PROCEDURE: allogeneic hematopoietic stem cell transplantation
PROCEDURE: peripheral blood stem cell transplantation
PROCEDURE: umbilical cord blood transplantation

Sponsor

University of California, San Francisco

Collaborators

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