# IMPROVE: Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy in ANCA Associated Systemic Vasculitis

> **NCT00307645** · PHASE3 · TERMINATED · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 160 (—)

## Conditions studied

- ANCA Associated Systemic Vasculitis Including Wegener's
- Granulomatosis and Microscopic Polyangiitis and
- Renal Limited Vasculitis

## Interventions

- **DRUG:** Cyclophosphamide
- **DRUG:** Mycophenolate mofetil
- **DRUG:** Azathioprine
- **DRUG:** Prednisone (and methylprednisolone)

## Key facts

- **NCT ID:** NCT00307645
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2003-05
- **Primary completion:** —
- **Final completion:** 2009-08
- **Target enrollment:** 160 (—)
- **Last updated:** 2006-04-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00307645

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00307645, "IMPROVE: Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy in ANCA Associated Systemic Vasculitis". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00307645. Licensed CC0.

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