# Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients

> **NCT00309569** · PHASE3 · COMPLETED · sponsor: **Austrian Breast & Colorectal Cancer Study Group** · enrollment: 429 (actual)

## Conditions studied

- Early Stage Breast Cancer

## Interventions

- **DRUG:** Cyclophosphamide
- **DRUG:** Methotrexate
- **DRUG:** Fluorouracil
- **DRUG:** Epirubicin
- **OTHER:** Surgery

## Key facts

- **NCT ID:** NCT00309569
- **Lead sponsor:** Austrian Breast & Colorectal Cancer Study Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 1991-10
- **Primary completion:** 2000-09
- **Final completion:** 2000-09
- **Target enrollment:** 429 (ACTUAL)
- **Last updated:** 2020-10-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00309569

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00309569, "Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients". Retrieved via AI Analytics 2026-07-02 from https://api.ai-analytics.org/clinical/NCT00309569. Licensed CC0.

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