# Hypertonic Resuscitation Following Severe Traumatic Brain Injury (TBI)

> **NCT00316004** · PHASE3 · TERMINATED · sponsor: **University of Washington** · enrollment: 1331 (actual)

## Conditions studied

- Brain Injuries, Traumatic

## Interventions

- **DRUG:** 7.5% Hypertonic Saline in 6% Dextran-70 (HSD)
- **DRUG:** 7.5% Hypertonic Saline (HS)
- **DRUG:** 0.9% Normal Saline (NS)

## Key facts

- **NCT ID:** NCT00316004
- **Lead sponsor:** University of Washington
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2006-05
- **Primary completion:** 2009-05
- **Final completion:** 2010-01
- **Target enrollment:** 1331 (ACTUAL)
- **Why stopped:** Futility
- **Last updated:** 2011-05-19

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00316004

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00316004, "Hypertonic Resuscitation Following Severe Traumatic Brain Injury (TBI)". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00316004. Licensed CC0.

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