# Hypertonic Resuscitation Following Traumatic Injury

> **NCT00316017** · PHASE3 · TERMINATED · sponsor: **University of Washington** · enrollment: 895 (actual)

## Conditions studied

- Shock, Traumatic

## Interventions

- **DRUG:** 7.5% hypertonic saline/6% Dextran-70 (HSD)
- **DRUG:** 7.5% hypertonic saline (HS)
- **DRUG:** 0.9% normal saline

## Key facts

- **NCT ID:** NCT00316017
- **Lead sponsor:** University of Washington
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2006-05
- **Primary completion:** 2009-08
- **Final completion:** 2009-08
- **Target enrollment:** 895 (ACTUAL)
- **Why stopped:** Futility \& potential safety concern (increased early mortality in the HS/HSD arms for those with no PRBC in 1st 24 hr, post-randomization subgp)
- **Last updated:** 2011-03-01

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00316017

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00316017, "Hypertonic Resuscitation Following Traumatic Injury". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT00316017. Licensed CC0.

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