# A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's Disease

> **NCT00322153** · PHASE3 · COMPLETED · sponsor: **Forest Laboratories** · enrollment: 677 (actual)

## Conditions studied

- Dementia of the Alzheimer's Type

## Interventions

- **DRUG:** memantine ER
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00322153
- **Lead sponsor:** Forest Laboratories
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-06
- **Primary completion:** 2007-10
- **Final completion:** 2008-01
- **Target enrollment:** 677 (ACTUAL)
- **Last updated:** 2010-09-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00322153

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00322153, "A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's Disease". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT00322153. Licensed CC0.

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