# Closed Loop Stimulation, Cognitive Performance, and Quality of Life in Pacemaker Patients

> **NCT00323661** · PHASE4 · COMPLETED · sponsor: **Biotronik SE & Co. KG** · enrollment: 405 (actual)

## Conditions studied

- Cardiac Pacing, Artificial

## Interventions

- **DEVICE:** Rate-adaptive pacemaker: accelerometer
- **DEVICE:** Rate-adaptive pacemaker: Closed Loop Stimulation

## Key facts

- **NCT ID:** NCT00323661
- **Lead sponsor:** Biotronik SE & Co. KG
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-05
- **Primary completion:** 2010-11
- **Final completion:** 2011-03
- **Target enrollment:** 405 (ACTUAL)
- **Last updated:** 2012-02-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00323661

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00323661, "Closed Loop Stimulation, Cognitive Performance, and Quality of Life in Pacemaker Patients". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00323661. Licensed CC0.

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