# 8-week Study to Evaluate Safety and Efficacy of Various Combinations of Valsartan, HCTZ, and Amlodipine in Patients With Moderate to Severe Hypertension

> **NCT00327587** · PHASE3 · COMPLETED · sponsor: **Novartis** · enrollment: 2279 (actual)

## Conditions studied

- Hypertension

## Interventions

- **DRUG:** Valsartan + amlodipine
- **DRUG:** Valsartan + HCTZ
- **DRUG:** Amlodipine + HCTZ
- **DRUG:** Valsartan + amlodipine + HCTZ

## Key facts

- **NCT ID:** NCT00327587
- **Lead sponsor:** Novartis
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-05
- **Primary completion:** 2007-08
- **Final completion:** 2007-08
- **Target enrollment:** 2279 (ACTUAL)
- **Last updated:** 2011-11-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00327587

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00327587, "8-week Study to Evaluate Safety and Efficacy of Various Combinations of Valsartan, HCTZ, and Amlodipine in Patients With Moderate to Severe Hypertension". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00327587. Licensed CC0.

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