# A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.

> **NCT00330460** · PHASE3 · COMPLETED · sponsor: **Amgen** · enrollment: 1189 (actual)

## Conditions studied

- Osteoporosis
- Osteopenia

## Interventions

- **DRUG:** Alendronate
- **DRUG:** Denosumab

## Key facts

- **NCT ID:** NCT00330460
- **Lead sponsor:** Amgen
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-05
- **Primary completion:** 2007-11
- **Final completion:** 2008-01
- **Target enrollment:** 1189 (ACTUAL)
- **Last updated:** 2011-01-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00330460

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00330460, "A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT00330460. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*