# Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic Lymphohistiocytosis

> **NCT00334672** · PHASE3 · UNKNOWN · sponsor: **Children's Cancer and Leukaemia Group** · enrollment: 288 (estimated)

## Conditions studied

- Nonneoplastic Condition

## Interventions

- **BIOLOGICAL:** anti-thymocyte globulin
- **DRUG:** busulfan
- **DRUG:** cyclophosphamide
- **DRUG:** cyclosporine
- **DRUG:** dexamethasone
- **DRUG:** etoposide
- **DRUG:** methotrexate
- **DRUG:** mycophenolate mofetil
- **DRUG:** therapeutic hydrocortisone
- **OTHER:** laboratory biomarker analysis
- **PROCEDURE:** allogeneic hematopoietic stem cell transplantation
- **PROCEDURE:** biopsy

## Key facts

- **NCT ID:** NCT00334672
- **Lead sponsor:** Children's Cancer and Leukaemia Group
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2006-03
- **Primary completion:** 2010-11
- **Final completion:** —
- **Target enrollment:** 288 (ESTIMATED)
- **Last updated:** 2013-09-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00334672

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00334672, "Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic Lymphohistiocytosis". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT00334672. Licensed CC0.

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