# Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly Diagnosed Localized Ewing's Sarcoma

> **NCT00334867** · PHASE3 · WITHDRAWN · sponsor: **Children's Oncology Group**

## Conditions studied

- Sarcoma

## Interventions

- **DRUG:** cyclophosphamide
- **DRUG:** dexrazoxane hydrochloride
- **DRUG:** doxorubicin hydrochloride
- **DRUG:** etoposide
- **DRUG:** ifosfamide
- **DRUG:** topotecan hydrochloride
- **DRUG:** vincristine sulfate
- **PROCEDURE:** conventional surgery
- **PROCEDURE:** radiation therapy

## Key facts

- **NCT ID:** NCT00334867
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2005-12
- **Primary completion:** 2006-01
- **Final completion:** —
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** withdrawn
- **Last updated:** 2013-06-28

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00334867

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00334867, "Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly Diagnosed Localized Ewing's Sarcoma". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT00334867. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*