# Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors

> **NCT00335556** · PHASE2 · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 291 (actual)

## Conditions studied

- Childhood Renal Cell Carcinoma
- Clear Cell Renal Cell Carcinoma
- Clear Cell Sarcoma of the Kidney
- Papillary Renal Cell Carcinoma
- Rhabdoid Tumor of the Kidney
- Stage I Renal Cell Cancer
- Stage I Renal Wilms Tumor
- Stage II Renal Cell Cancer
- Stage II Renal Wilms Tumor
- Stage III Renal Cell Cancer
- Stage III Renal Wilms Tumor
- Stage IV Renal Cell Cancer
- Stage IV Renal Wilms Tumor

## Interventions

- **DRUG:** Doxorubicin Hydrochloride
- **DRUG:** Irinotecan Hydrochloride
- **PROCEDURE:** Conventional Surgery
- **DRUG:** Cyclophosphamide
- **DRUG:** Etoposide
- **DRUG:** Carboplatin
- **BIOLOGICAL:** Dactinomycin
- **DRUG:** Vincristine Sulfate
- **RADIATION:** Radiation Therapy
- **OTHER:** Laboratory Biomarker Analysis

## Key facts

- **NCT ID:** NCT00335556
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-06
- **Primary completion:** 2015-12
- **Final completion:** —
- **Target enrollment:** 291 (ACTUAL)
- **Last updated:** 2017-07-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00335556

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00335556, "Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors". Retrieved via AI Analytics 2026-06-13 from https://api.ai-analytics.org/clinical/NCT00335556. Licensed CC0.

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