# Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma

> **NCT00338377** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 1230 (actual)

## Conditions studied

- Melanoma

## Interventions

- **BIOLOGICAL:** Dendritic Cell Immunization
- **DRUG:** Cyclophosphamide
- **DRUG:** Fludarabine
- **BIOLOGICAL:** T-Cells
- **BIOLOGICAL:** Interleukin-2
- **DRUG:** Mesna
- **BIOLOGICAL:** Intrathecal T-Cells
- **BIOLOGICAL:** Intrathecal Interleukin-2

## Key facts

- **NCT ID:** NCT00338377
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2006-02-01
- **Primary completion:** 2030-02-28
- **Final completion:** 2030-02-28
- **Target enrollment:** 1230 (ACTUAL)
- **Last updated:** 2026-03-20

## Collaborators

- [object Object]
- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00338377

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00338377, "Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT00338377. Licensed CC0.

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