# Randomized Trial Comparing 3 Routes of Delivering Lorazepam to Children.

> **NCT00343096** · PHASE3 · TERMINATED · sponsor: **Kamuzu University of Health Sciences** · enrollment: 800 (actual)

## Conditions studied

- Status Epilepticus
- Convulsions

## Interventions

- **DRUG:** Lorazepam

## Key facts

- **NCT ID:** NCT00343096
- **Lead sponsor:** Kamuzu University of Health Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2006-06
- **Primary completion:** 2009-03
- **Final completion:** 2009-03
- **Target enrollment:** 800 (ACTUAL)
- **Why stopped:** The buccal arm of the study was 30% less effective in stopping seizures within 10 minutes compared with the IV dose. This met a stopping rule for the study
- **Last updated:** 2012-07-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00343096

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00343096, "Randomized Trial Comparing 3 Routes of Delivering Lorazepam to Children.". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00343096. Licensed CC0.

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