# Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer

> **NCT00343863** · NA · COMPLETED · sponsor: **University of Washington** · enrollment: 41 (actual)

## Conditions studied

- Male Breast Cancer
- Nausea and Vomiting
- Stage I Breast Cancer
- Stage II Breast Cancer
- Stage IIIA Breast Cancer

## Interventions

- **DRUG:** palonosetron hydrochloride
- **DRUG:** cyclophosphamide
- **DRUG:** dexamethasone
- **DRUG:** doxorubicin hydrochloride
- **PROCEDURE:** quality-of-life assessment
- **PROCEDURE:** nausea and vomiting therapy
- **PROCEDURE:** management of therapy complications
- **DRUG:** ondansetron hydrochloride
- **OTHER:** survey administration

## Key facts

- **NCT ID:** NCT00343863
- **Lead sponsor:** University of Washington
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-01
- **Primary completion:** 2010-12
- **Final completion:** 2010-12
- **Target enrollment:** 41 (ACTUAL)
- **Last updated:** 2017-07-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00343863

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00343863, "Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT00343863. Licensed CC0.

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