# Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases

> **NCT00351975** · PHASE1 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 56 (actual)

## Conditions studied

- Accelerated Phase of Disease
- Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11
- Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11
- Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1
- Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL
- Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA
- Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative
- Blastic Phase
- Chronic Myelogenous Leukemia, BCR-ABL1 Positive
- Chronic Myelomonocytic Leukemia
- de Novo Myelodysplastic Syndrome
- Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable
- Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia
- Previously Treated Myelodysplastic Syndrome
- Primary Myelofibrosis
- Recurrent Adult Acute Lymphoblastic Leukemia
- Recurrent Adult Acute Myeloid Leukemia
- Recurrent Disease
- Secondary Acute Myeloid Leukemia
- Secondary Myelodysplastic Syndrome

## Interventions

- **DRUG:** Belinostat
- **DRUG:** Azacitidine
- **OTHER:** Laboratory Biomarker Analysis

## Key facts

- **NCT ID:** NCT00351975
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-06
- **Primary completion:** 2013-03
- **Final completion:** 2013-03
- **Target enrollment:** 56 (ACTUAL)
- **Last updated:** 2014-12-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00351975

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00351975, "Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00351975. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*