# A Phase III, Randomized, Study of Aspirin and Esomeprazole Chemoprevention in Barrett's Metaplasia

> **NCT00357682** · PHASE3 · COMPLETED · sponsor: **University of Oxford** · enrollment: 2557 (actual)

## Conditions studied

- Esophageal Cancer
- Precancerous Condition

## Interventions

- **DRUG:** Esomeprazole
- **DRUG:** Esomeprazole
- **DRUG:** Aspirin

## Key facts

- **NCT ID:** NCT00357682
- **Lead sponsor:** University of Oxford
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-03-10
- **Primary completion:** 2017-05-31
- **Final completion:** 2017-05-31
- **Target enrollment:** 2557 (ACTUAL)
- **Last updated:** 2025-05-01

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00357682

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00357682, "A Phase III, Randomized, Study of Aspirin and Esomeprazole Chemoprevention in Barrett's Metaplasia". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT00357682. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*