# Effect of Cyclosporine Therapy on Gene Expression in Patients With Large Granular Lymphocyte Leukemia

> **NCT00363779** · PHASE2 · TERMINATED · sponsor: **National Cancer Institute (NCI)** · enrollment: 5 (actual)

## Conditions studied

- Large Granular Lymphocytic Leukemia
- LGL Leukemia

## Interventions

- **DRUG:** Cyclosporine
- **GENETIC:** Gene expression analysis
- **GENETIC:** Microarray analysis
- **OTHER:** Laboratory biomarker analysis

## Key facts

- **NCT ID:** NCT00363779
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2006-06
- **Primary completion:** 2010-11
- **Final completion:** 2010-11
- **Target enrollment:** 5 (ACTUAL)
- **Why stopped:** Study terminated due to low accrual and the investigator left the NIH.
- **Last updated:** 2015-07-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00363779

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00363779, "Effect of Cyclosporine Therapy on Gene Expression in Patients With Large Granular Lymphocyte Leukemia". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00363779. Licensed CC0.

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