# Lapatinib and Radiation Therapy in Treating Patients With Locally Recurrent or Chemotherapy-Refractory Locally Advanced or Metastatic Breast Cancer

> **NCT00379509** · PHASE1 · COMPLETED · sponsor: **UNC Lineberger Comprehensive Cancer Center** · enrollment: 20 (actual)

## Conditions studied

- Breast Cancer

## Interventions

- **DRUG:** lapatinib ditosylate
- **GENETIC:** TdT-mediated dUTP nick end labeling assay
- **GENETIC:** gene expression analysis
- **GENETIC:** microarray analysis
- **OTHER:** immunohistochemistry staining method
- **PROCEDURE:** biopsy
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00379509
- **Lead sponsor:** UNC Lineberger Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-04
- **Primary completion:** 2010-06
- **Final completion:** 2012-08
- **Target enrollment:** 20 (ACTUAL)
- **Last updated:** 2017-03-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00379509

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00379509, "Lapatinib and Radiation Therapy in Treating Patients With Locally Recurrent or Chemotherapy-Refractory Locally Advanced or Metastatic Breast Cancer". Retrieved via AI Analytics 2026-08-02 from https://api.ai-analytics.org/clinical/NCT00379509. Licensed CC0.

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