# Improving Outcomes in Patients With Kidney Disease Due to Diabetes

> **NCT00381134** · PHASE2 · COMPLETED · sponsor: **National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)** · enrollment: 92 (estimated)

## Conditions studied

- Diabetes
- Kidney Disease
- Hypertension

## Interventions

- **DRUG:** losartan 100 mg orally once daily
- **DRUG:** spironolactone 25 mg orally once daily
- **DRUG:** placebo once orally once daily

## Key facts

- **NCT ID:** NCT00381134
- **Lead sponsor:** National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2003-07
- **Primary completion:** —
- **Final completion:** 2006-12
- **Target enrollment:** 92 (ESTIMATED)
- **Last updated:** 2010-03-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00381134

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00381134, "Improving Outcomes in Patients With Kidney Disease Due to Diabetes". Retrieved via AI Analytics 2026-09-27 from https://api.ai-analytics.org/clinical/NCT00381134. Licensed CC0.

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