Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia
Conditions
- B-cell Childhood Acute Lymphoblastic Leukemia
- L1 Childhood Acute Lymphoblastic Leukemia
- L2 Childhood Acute Lymphoblastic Leukemia
- Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions
- DRUG: vincristine sulfate
- DRUG: prednisone
- DRUG: doxorubicin hydrochloride
- DRUG: pegaspargase
- DRUG: cytarabine
- DRUG: methotrexate
- DRUG: dexamethasone
- DRUG: etoposide
- DRUG: cyclophosphamide
- DRUG: leucovorin calcium
- BIOLOGICAL: filgrastim
- DRUG: asparaginase
- DRUG: mercaptopurine
Sponsor
Children's Oncology Group
Collaborators