# PTK787/ZK 222584 in Combination With Temozolomide and Radiation in Patients With Glioblastoma Taking Enzyme-Inducing Anti-Epileptic Drugs

> **NCT00385853** · PHASE1 · COMPLETED · sponsor: **Massachusetts General Hospital** · enrollment: 19 (actual)

## Conditions studied

- Glioblastoma

## Interventions

- **DRUG:** PTK787/ZK 222584
- **DRUG:** Temozolomide
- **PROCEDURE:** Radiation Therapy

## Key facts

- **NCT ID:** NCT00385853
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-09
- **Primary completion:** 2011-09
- **Final completion:** 2011-09
- **Target enrollment:** 19 (ACTUAL)
- **Last updated:** 2013-10-21

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00385853

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00385853, "PTK787/ZK 222584 in Combination With Temozolomide and Radiation in Patients With Glioblastoma Taking Enzyme-Inducing Anti-Epileptic Drugs". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00385853. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*