# Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence

> **NCT00390923** · NA · TERMINATED · sponsor: **Centre for Addiction and Mental Health** · enrollment: 40 (estimated)

## Conditions studied

- Nicotine Dependence

## Interventions

- **DRUG:** Selegiline + nicotine replacement therapy
- **DRUG:** placebo + nicotine replacement therapy

## Key facts

- **NCT ID:** NCT00390923
- **Lead sponsor:** Centre for Addiction and Mental Health
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-07
- **Primary completion:** 2008-04
- **Final completion:** 2008-04
- **Target enrollment:** 40 (ESTIMATED)
- **Why stopped:** Preliminary results did not support the utility of combining selegeline + NRT.
- **Last updated:** 2013-08-29

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00390923

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00390923, "Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence". Retrieved via AI Analytics 2026-08-03 from https://api.ai-analytics.org/clinical/NCT00390923. Licensed CC0.

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