# The CRISIS Prevention Study

> **NCT00395161** · PHASE3 · TERMINATED · sponsor: **Michael Dean** · enrollment: 293 (actual)

## Conditions studied

- Sepsis

## Interventions

- **DRUG:** Metoclopramide
- **DRUG:** Zinc
- **DIETARY_SUPPLEMENT:** Glutamine
- **DRUG:** Selenium
- **OTHER:** saline
- **OTHER:** sterile water
- **OTHER:** selenium
- **DIETARY_SUPPLEMENT:** whey-protein

## Key facts

- **NCT ID:** NCT00395161
- **Lead sponsor:** Michael Dean
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-04
- **Primary completion:** 2009-11
- **Final completion:** 2009-11
- **Target enrollment:** 293 (ACTUAL)
- **Why stopped:** Terminated for futility on 11/30/09 based on the recommendation of the DSMB
- **Last updated:** 2013-04-18

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00395161

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00395161, "The CRISIS Prevention Study". Retrieved via AI Analytics 2026-08-11 from https://api.ai-analytics.org/clinical/NCT00395161. Licensed CC0.

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