# Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation

> **NCT00402337** · PHASE2 · COMPLETED · sponsor: **Ironwood Pharmaceuticals, Inc.** · enrollment: 310 (actual)

## Conditions studied

- Chronic Constipation

## Interventions

- **DRUG:** linaclotide acetate
- **DRUG:** Matching placebo

## Key facts

- **NCT ID:** NCT00402337
- **Lead sponsor:** Ironwood Pharmaceuticals, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-11
- **Primary completion:** 2007-12
- **Final completion:** 2008-02
- **Target enrollment:** 310 (ACTUAL)
- **Last updated:** 2013-03-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00402337

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00402337, "Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00402337. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*