# Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease

> **NCT00404131** · PHASE3 · COMPLETED · sponsor: **Merck Sharp & Dohme LLC** · enrollment: 500 (estimated)

## Conditions studied

- Dry Eye Disease

## Interventions

- **DRUG:** diquafosol tetrasodium (INS365) Ophthalmic Solution

## Key facts

- **NCT ID:** NCT00404131
- **Lead sponsor:** Merck Sharp & Dohme LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2001-03
- **Primary completion:** 2001-12
- **Final completion:** 2001-12
- **Target enrollment:** 500 (ESTIMATED)
- **Last updated:** 2016-11-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00404131

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00404131, "Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT00404131. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*