# Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma

> **NCT00408005** · PHASE3 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 1895 (actual)

## Conditions studied

- T Acute Lymphoblastic Leukemia
- T Lymphoblastic Lymphoma

## Interventions

- **DRUG:** Asparaginase
- **DRUG:** Cyclophosphamide
- **DRUG:** Cytarabine
- **DRUG:** Daunorubicin Hydrochloride
- **DRUG:** Dexamethasone
- **DRUG:** Doxorubicin Hydrochloride
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Leucovorin Calcium
- **DRUG:** Mercaptopurine
- **DRUG:** Methotrexate
- **DRUG:** Nelarabine
- **DRUG:** Pegaspargase
- **DRUG:** Prednisone
- **RADIATION:** Radiation Therapy
- **DRUG:** Thioguanine
- **DRUG:** Vincristine Sulfate

## Key facts

- **NCT ID:** NCT00408005
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-01-30
- **Primary completion:** 2017-09-30
- **Final completion:** 2025-03-31
- **Target enrollment:** 1895 (ACTUAL)
- **Last updated:** 2025-04-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00408005

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00408005, "Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00408005. Licensed CC0.

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