# Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)

> **NCT00412360** · PHASE3 · COMPLETED · sponsor: **Medical College of Wisconsin** · enrollment: 224 (actual)

## Conditions studied

- Acute Myelogenous Leukemia
- Acute Lymphocytic Leukemia
- Chronic Myelogenous Leukemia
- Myelodysplastic Syndrome
- Natural Killer Cell Lymphoblastic Leukemia/Lymphoma

## Interventions

- **BIOLOGICAL:** Single Umbilical Cord Blood Unit Transplant
- **BIOLOGICAL:** Double Umbilical Cord Blood Unit Transplant
- **RADIATION:** Total Body Irradiation
- **DRUG:** Cyclophosphamide
- **DRUG:** Fludarabine
- **DRUG:** Cyclosporine A
- **DRUG:** Mycophenolate Mofetil

## Key facts

- **NCT ID:** NCT00412360
- **Lead sponsor:** Medical College of Wisconsin
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-12
- **Primary completion:** 2014-03
- **Final completion:** 2014-10
- **Target enrollment:** 224 (ACTUAL)
- **Last updated:** 2021-10-28

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00412360

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00412360, "Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00412360. Licensed CC0.

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