# A Multicenter Study to Compare Multiple Doses of Intravitreal Microplasmin Versus Sham Injection for Treatment of Patients With Diabetic Macular Edema (DME)

> **NCT00412451** · PHASE2 · COMPLETED · sponsor: **ThromboGenics** · enrollment: 51 (actual)

## Conditions studied

- Diabetic Macular Edema

## Interventions

- **DRUG:** ocriplasmin
- **OTHER:** Sham injection

## Key facts

- **NCT ID:** NCT00412451
- **Lead sponsor:** ThromboGenics
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-12
- **Primary completion:** 2010-01
- **Final completion:** 2010-03
- **Target enrollment:** 51 (ACTUAL)
- **Last updated:** 2014-12-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00412451

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00412451, "A Multicenter Study to Compare Multiple Doses of Intravitreal Microplasmin Versus Sham Injection for Treatment of Patients With Diabetic Macular Edema (DME)". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT00412451. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*