# A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) Pain

> **NCT00418782** · PHASE2 · TERMINATED · sponsor: **Pfizer** · enrollment: 212 (actual)

## Conditions studied

- Osteoarthritis

## Interventions

- **DRUG:** naproxen
- **DRUG:** CE-224535
- **DRUG:** placebo

## Key facts

- **NCT ID:** NCT00418782
- **Lead sponsor:** Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-01
- **Primary completion:** —
- **Final completion:** 2007-08
- **Target enrollment:** 212 (ACTUAL)
- **Why stopped:** Results of interim analysis indicate lack of efficacy when compared to placebo.
- **Last updated:** 2018-12-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00418782

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00418782, "A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) Pain". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00418782. Licensed CC0.

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